Homology-based inference sets the bar high for protein function prediction

ProSNet: integrating homology with molecular networks for protein function prediction

Automated annotation of protein function has become a critical task in the post-genomic era. Network-based approaches and homology-based approaches have been widely used and recently tested in large-scale community-wide assessment experiments. It is natural to integrate network data with homology information to further improve the predictive performance. However, integrating these two heterogen...

Statistical inference for template-based protein structure prediction

...................................................................I Acknowledgements.....................................................II List of Figures..........................................................VI List of Tables............................................................IX

OR manager of the year sets--and meets--high bar.

AGenDA: homology-based gene prediction

We present a www server for homology-based gene prediction. The user enters a pair of evolutionary related genomic sequences, for example from human and mouse. Our software system uses CHAOS and DIALIGN to calculate an alignment of the input sequences and then searches for conserved splicing signals and start/stop codons around regions of local sequence similarity. This way, candidate exons are...

Bar-natan’s Khovanov Homology for Coloured Links

Using Bar-Natan’s Khovanov homology we define a homology theory for links whose components are labelled by irreducible representations of Uq(sl2). We then compute this explicitly.